Article
The effects of puerarin on CYP2D6 and CYP1A2 activities in vivo.
Archives of pharmacal research - 1 Feb 2010
Zheng Jiao, Chen Bin, Jiang Bing, Zeng Ling, Tang Zhi-Rong, Fan Lan, Zhou Hong-Hao
Abstract excerpt
Ge-gen (Radix Puerariae) is used in traditional oriental medicine for various medicinal purposes. The drug is the root of a wild leguminous creeper, Pueraria lobata (Willd) Ohwi. It possesses a high content of avonoid derivatives, the most abundant of which is puerarin. Our goal was to find the effect of puerarin on cytochrome P450 enzymes in vivo. The study was conducted in 18 male volunteers of different...
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