Article
Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects.
British journal of pharmacology - 1 Aug 2008
Mohammed Abdul M I, Jiang X, Williams K M, Day R O, Roufogalis B D, Liauw W S, Xu H, McLachlan A J
Abstract excerpt
BACKGROUND AND PURPOSE: Patients commonly take complementary medicines in conjunction with warfarin yet evidence supporting the safety or the risk of a herb-drug interaction is lacking. The aim of this study was to investigate the possible impact of two commonly used herbal medicines, garlic and cranberry, on the pharmacokinetics and pharmacodynamics of warfarin in healthy male subjects. EXPERIMENTAL APPROACH: An...
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