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The in silico and in vivo evaluation of puerarin against Alzheimer's disease

1 Jan 2019

Abstract excerpt

The root of Pueraria lobata has been utilized as a food source for thousands of years in China. Puerarin is the major bioactive and the most abundant secondary metabolite obtained from the root of P. lobata. The potential therapeutic effect of puerarin against Alzheimer's disease was screened by in silico methods and confirmed by the amyloid β-peptide-induced Alzheimer's disease (AD) rat model. The in silico...

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PMID: 30675620
DOI: 10.1039/c8fo01696h

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