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Article

Inhibitor of growth tumor suppressors in cancer progression.

Cellular and molecular life sciences : CMLS - 1 Jun 2010

Piche Brad, Li Gang

Abstract excerpt

The inhibitor of growth (ING) family of tumor suppressors has five members and is implicated in the control of apoptosis, senescence, DNA repair, and cancer progression. However, little is known about ING activity in the regulation of cancer progression. ING members and splice variants seem to behave differently with respect to cancer invasion and metastasis. Interaction with histone trimethylated at lysine 4...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20195696
DOI: 10.1007/s00018-010-0312-z
PMCID: PMC11115670

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Inhibitor of growth tumor suppressors in cancer progression.PMID 20195696Read ↗

Biological functions of the ING family tumor suppressors.Semantic proximity Read ↗

The new tumor suppressor genes ING: Genomic structure and status in cancerSemantic proximity Read ↗

Expression profiles of mRNA transcript variants encoding the human inhibitor of growth tumor suppressor gene family in normal and neoplastic tissues.Semantic proximity Read ↗

Function of the ING family of PHD proteins in cancer.Semantic proximity Read ↗

The role of the tumour suppressor p33 ING1b in human neoplasia.Semantic proximity Read ↗

The tumor suppressor ING3 is degraded by SCF(Skp2)-mediated ubiquitin-proteasome system.Semantic proximity Read ↗

Functional impact of cancer-associated mutations in the tumor suppressor protein ING4.Semantic proximity Read ↗

Tumor-specific mutation and downregulation of ING5 detected in oral squamous cell carcinoma.Semantic proximity Read ↗

Nuclear localization of ING3 is required to suppress melanoma cell migration, invasion and angiogenesis.Semantic proximity Read ↗

CG7379/ING1 suppress cancer cell invasion by maintaining cell-cell junction integritySemantic proximity Read ↗

ING function in apoptosis in diverse model systems.Semantic proximity Read ↗

ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth.Semantic proximity Read ↗

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