Article
Tumor-specific mutation and downregulation of ING5 detected in oral squamous cell carcinoma.
International journal of cancer - 1 Nov 2010
Cengiz Beyhan, Gunduz Esra, Gunduz Mehmet, Beder Levent Bekir, Tamamura Ryo, Bagci Cahit, Yamanaka Noboru, Shimizu Kenji, Nagatsuka Hitoshi
Abstract excerpt
Our previous study showed high frequency of allelic loss at chromosome 2q37 region in oral cancer. This location contains several candidate tumor suppressor genes such as PPP1R7, ILKAP, DTYMK and ING5. We previously showed 3 members of inhibitor of growth (ING) family, ING1, ING3 and ING4 as tumo...
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