Article
ING function in apoptosis in diverse model systems.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Feb 2009
Shah Sitar, Smith Heather, Feng Xiaolan, Rancourt Derrick E, Riabowol Karl
Abstract excerpt
Genetic studies in model organisms have shown that programmed cell death (apoptosis) plays a significant role during development, where a deficiency in apoptosis results in severe and diverse diseases. Dysregulation of apoptosis also contributes to a variety of human diseases, such as cancer and autoimmune diseases. ING family proteins (ING1-ING5) are involved in many cellular processes, and appear to play a...
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