ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth.

doi:10.1038/onc.2013.145

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Article

ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth.

Oncogene - 10 Apr 2014

Moreno A, Soleto I, García-Sanz P, Moreno-Bueno G, Palmero I

Abstract excerpt

ING proteins have an essential role in the control of a variety of cellular functions whose deregulation is associated with tumor formation and dissemination, such as proliferation, apoptosis, senescence or invasion. Accordingly, loss of function of ING proteins is a frequent event in many types of human tumors. In this report, we have studied the function of ING4, a member of the ING family of tumor suppressors,...

Topics

Animals
Blotting, Western
Cell Cycle Proteins
Cell Line
Cell Proliferation
Chromatin Immunoprecipitation
Cytokines
Disease Progression
Enzyme-Linked Immunosorbent Assay
Fibroblasts
Heterografts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homeodomain Proteins

Humans

Immunohistochemistry

Mice

Mice, Nude

Neoplasms, Experimental

Oligonucleotide Array Sequence Analysis

Source

Open in PubMed

Identifiers

PMID: 23604125
DOI: 10.1038/onc.2013.145

Genes

ING4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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