ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth.

Abstract excerpt

ING proteins have an essential role in the control of a variety of cellular functions whose deregulation is associated with tumor formation and dissemination, such as proliferation, apoptosis, senescence or invasion. Accordingly, loss of function of ING proteins is a frequent event in many types of human tumors. In this report, we have studied the function of ING4, a member of the ING family of tumor suppressors,...

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