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Article

The tumor suppressor ING3 is degraded by SCF(Skp2)-mediated ubiquitin-proteasome system.

Oncogene - 11 Mar 2010

Chen G, Wang Y, Garate M, Zhou J, Li G

Abstract excerpt

The inhibitor of growth family member 3 (ING3) has been shown to modulate transcription, cell cycle control and apoptosis. We previously reported that nuclear ING3 expression was remarkably reduced in melanomas, which correlated with a poorer patient survival, suggesting that decreased ING3 expression may be associated with melanoma progression. However, the mechanism of diminished ING3 expression in melanoma is...

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Source

Identifiers

PMID: 19935701
DOI: 10.1038/onc.2009.424

Genes

ING3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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