Article
Single nucleotide polymorphisms in genes that are associated with a modified response to statin therapy: the Rotterdam Study.
The pharmacogenomics journal - 1 Feb 2011
de Keyser C E, Eijgelsheim M, Hofman A, Sijbrands E J G, Maitland-van der Zee A-H, van Duijn C M, Uitterlinden A G, Witteman J C M, Ch Stricker B H
Abstract excerpt
The objective of this study was to investigate whether common variation in genes involved in lipid metabolism modify the effect of statins on serum total cholesterol concentration. Statin users were identified in the Rotterdam Study, a prospective population-based cohort study of subjects >55 yea...
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