Article
Exclusion of Kif1c as a candidate gene for anthrax toxin susceptibility.
Microbial pathogenesis - 1 May 2010
Nakajima Kazuo, Tanaka Yosuke
Abstract excerpt
Different strains of mice possess varying degrees of susceptibility to anthrax lethal toxin (LT). Previous studies have suggested a responsible locus Ltxs1 that contains 10 or more known genes, but functional relevance has been reported for two genes, Kif1c and Nalp1b. In this study, we attempted to determine the involvement of Kif1c in anthrax susceptibility using Kif1c knockout mice. We established Kif1c...
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