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Article

Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of Nalp1b/Nlrp1b.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2010

Terra Jill K, Cote Christopher K, France Bryan, Jenkins Amy L, Bozue Joel A, Welkos Susan L, LeVine Steven M, Bradley Kenneth A

Abstract excerpt

Pathogenesis of Bacillus anthracis is associated with the production of lethal toxin (LT), which activates the murine Nalp1b/Nlrp1b inflammasome and induces caspase-1-dependent pyroptotic death in macrophages and dendritic cells. In this study, we investigated the effect of allelic variation of N...

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Source

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Identifiers

PMID: 19949100
DOI: 10.4049/jimmunol.0903114
PMCID: PMC2811128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19949100-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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