Article
Quickening the pace of anthrax research: three advances point towards possible therapies.
Trends in microbiology - 1 Feb 2002
Chaudry G Jilani, Moayeri Mahtab, Liu Shihui, Leppla Stephen H
Abstract excerpt
Anthrax toxin is the dominant virulence factor of Bacillus anthracis and drugs blocking its action could therefore have therapeutic benefit. Three recent papers suggest new ways to inhibit the toxin. Identification of the cell surface toxin receptor could lead to the design of binding competitors and receptor decoys. Determination of the crystal structure of the lethal factor protease will facilitate ongoing...
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