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Article

An anthrax lethal factor mutant that is defective at causing pyroptosis retains proapoptotic activity.

The FEBS journal - 1 Jan 2010

Ngai Stephanie, Batty Sarah, Liao Kuo-Chieh, Mogridge Jeremy

Abstract excerpt

Anthrax lethal toxin triggers death in some cell types, such as macrophages, and causes a variety of cellular dysfunctions in others. Collectively, these effects dampen the innate and adaptive immune systems to allow Bacillus anthracis to survive and proliferate in the mammalian host. The diverse effects caused by the toxin have in part been attributed to its interference with signaling pathways in target cells....

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Source

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Identifiers

PMID: 19922472
DOI: 10.1111/j.1742-4658.2009.07458.x
PMCID: PMC2805769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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