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Article

Glutathione S-transferase polymorphisms are associated with survival in anaplastic glioma patients.

Cancer - 1 May 2010

Kilburn Lindsay, Okcu M Fatih, Wang Tao, Cao Yumei, Renfro-Spelman Amy, Aldape Kenneth D, Gilbert Mark R, Bondy Melissa

Abstract excerpt

BACKGROUND: Glutathione S-transferases (GSTs) are polymorphic enzymes that are responsible for glutathione conjugation of alkylators and scavenging of free radicals created by radiation. GST polymorphisms may result in altered or absent enzyme activity and have been associated with survival in patients with cancer. The authors of this report hypothesized that patients with anaplastic glioma (AG) who have GST...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 20187096
DOI: 10.1002/cncr.25006
PMCID: PMC2861043

Genes

GSTP1
GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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