Article
Glutathione S-transferase polymorphisms are associated with survival in anaplastic glioma patients.
Cancer - 1 May 2010
Kilburn Lindsay, Okcu M Fatih, Wang Tao, Cao Yumei, Renfro-Spelman Amy, Aldape Kenneth D, Gilbert Mark R, Bondy Melissa
Abstract excerpt
BACKGROUND: Glutathione S-transferases (GSTs) are polymorphic enzymes that are responsible for glutathione conjugation of alkylators and scavenging of free radicals created by radiation. GST polymorphisms may result in altered or absent enzyme activity and have been associated with survival in pa...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
