Article
Glutathione S-transferase M1, T1, and P1 polymorphisms and survival among lung cancer patients.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2003
Sweeney Carol, Nazar-Stewart Valle, Stapleton Patricia L, Eaton David L, Vaughan Thomas L
Abstract excerpt
Glutathione S-transferase (GST) enzymes detoxify therapeutic drugs and reactive oxidants, so GST polymorphisms may influence survival after diagnosis of cancer. We evaluated survival according to GST polymorphisms in a population-based series of lung cancer patients. The study subjects (n = 274) were men diagnosed with lung cancer from 1993 through 1996 who participated in a case control study and provided a...
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