Article
Effect of glutathione S-transferases on the survival of patients with acute myeloid leukaemia.
European journal of pharmacology - 1 Mar 2002
Autrup Judith L, Hokland Peter, Pedersen Lars, Autrup Herman
Abstract excerpt
The objective of the study was to investigate the effect of genetic polymorphisms in glutathione S-transferases (GST) on the survival of acute myeloid leukaemia patients receiving adriamycin induction therapy. A total of 89 patients were included in the study. Patients who carried at least one GSTM1 allele had trend towards a better survival (mortality rate ratio (RR) 0.588; 95% CI 0.334-1.036) than GSTM1*0/0...
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