Article
An updated pooled analysis of glutathione S-transferase genotype polymorphisms and risk of adult gliomas.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Yao Lei, Ji Guixiang, Gu Aihua, Zhao Peng, Liu Ning
Abstract excerpt
OBJECTIVE: Glutathione S-transferases (GSTs) are multifunctional enzymes that play a crucial role in the detoxification of both the endogenous products of oxidative stress and exogenous carcinogens. Recent studies investigating the association between genetic polymorphisms in GSTs and the risk of adult brain tumors have reported conflicting results. The rationale of this pooled analysis was to determine whether...
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