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Article

Glutathione S-transferase polymorphisms and survival in primary malignant glioma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2004

Okcu M Fatih, Selvan Mano, Wang Li-E, Stout Linda, Erana Rodrigo, Airewele Gladstone, Adatto Phyllis, Hess Kenneth, Ali-Osman Francis, Groves Morris, Yung Alfred W K, Levin Victor A, Wei Qingyi, Bondy Melissa

Abstract excerpt

PURPOSE: The purpose of this research was to investigate the relationship between glutathione S-transferase (GST) polymorphisms and survival, and chemotherapy-related toxicity in 278 glioma patients. EXPERIMENTAL DESIGN: We determined genetic variants for GSTM1, GSTT1, and GSTP1 enzymes by PCR and restriction fragment length polymorphisms. We conducted Kaplan-Meier and Cox-proportional hazard analyses to examine...

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Source

Identifiers

PMID: 15102663
DOI: 10.1158/1078-0432.ccr-03-0053

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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