Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Mar 2001

Davies S M, Robison L L, Buckley J D, Tjoa T, Woods W G, Radloff G A, Ross J A, Perentesis J P

Abstract excerpt

PURPOSE: Glutathione S-transferase theta (GSTT1) and mu (GSTM1) genes are polymorphic, the genes being absent in approximately 15% and 50% of the population, respectively. Because glutathione S-transferases may be involved in the metabolism of chemotherapy drugs, we hypothesized that presence or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Combined Chemotherapy Protocols
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to Leukemia, Myeloid

Share to Prognosis

Share to Recurrence

Share to Risk Assessment

Share to Survival Analysis

Source

Identifiers

PMID: 11230469
DOI: 10.1200/JCO.2001.19.5.1279

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11230469-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia.PMID 11230469Read ↗

Glutathione S-transferase polymorphisms in children with myeloid leukemia: a Children's Cancer Group study.Semantic proximity Read ↗

Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia.Semantic proximity Read ↗

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia.Semantic proximity Read ↗

Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Polymorphisms of CYP1A1 and glutathione S-transferase and susceptibility to adult acute myeloid leukemia.Semantic proximity Read ↗

Prognostic significance of the null genotype of glutathione S-transferase-T1 in patients with acute myeloid leukemia: increased early death after chemotherapy.Semantic proximity Read ↗

GSTT1 and GSTM1 polymorphisms predict treatment outcome for acute myeloid leukemia: a systematic review and meta-analysis.Semantic proximity Read ↗

Glutathione S-transferase genotypes in children who develop treatment-related acute myeloid malignancies.Semantic proximity Read ↗

Increased risk for acute myeloid leukaemia in individuals with glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) gene defects.Semantic proximity Read ↗

Meta-analysis study of glutathione-S-transferases (GSTM1, GSTP1, and GSTT1) gene polymorphisms and risk of acute myeloid leukemia.Semantic proximity Read ↗

DNA repair polymorphisms and outcome of chemotherapy for acute myelogenous leukemia: a report from the Children's Oncology Group.Semantic proximity Read ↗

[The effects of glutathione S-transferase (GSTT1 and GSTM1) genes polymorphisms on treatment efficacy and prognosis of acute myeloid leukemia].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.