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Article

Nav2 is necessary for cranial nerve development and blood pressure regulation.

Neural development - 25 Feb 2010

McNeill Elizabeth M, Roos Kenneth P, Moechars Dieder, Clagett-Dame Margaret

Abstract excerpt

BACKGROUND: All-trans retinoic acid (atRA) is required for nervous system development, including the developing hindbrain region. Neuron navigator 2 (Nav2) was first identified as an atRA-responsive gene in human neuroblastoma cells (retinoic acid-induced in neuroblastoma 1, Rainb1), and is required for atRA-mediated neurite outgrowth. In this paper, we explore the importance of Nav2 in nervous system development...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20184720
DOI: 10.1186/1749-8104-5-6
PMCID: PMC2843687

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