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Loss of Neuron Navigator 2 Impairs Brain and Cerebellar Development

26 Feb 2022

Abstract excerpt

Cerebellar hypoplasia and dysplasia encompass a group of clinically and genetically heterogeneous disorders frequently associated with neurodevelopmental impairment. The Neuron Navigator 2 (NAV2) gene (MIM: 607,026) encodes a member of the Neuron Navigator protein family, widely expressed within the central nervous system (CNS), and particularly abundant in the developing cerebellum. Evidence across different...

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PMID: 35218524
DOI: 10.1007/s12311-022-01379-3

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