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Article

Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice.

Proceedings of the National Academy of Sciences of the United States of America - 18 Feb 2003

Vermot Julien, Niederreither Karen, Garnier Jean-Marie, Chambon Pierre, Dollé Pascal

Abstract excerpt

Retinoic acid (RA), the active derivative of vitamin A, is involved in various developmental and homeostatic processes. To define whether certain developmental events are particularly sensitive to a decrease in embryonic RA levels, we generated mice bearing a hypomorphic allele of the RA-synthesi...

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Identifiers

PMID: 12563036
DOI: 10.1073/pnas.0437920100
PMCID: PMC149907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12563036-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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