The septic shock-associated IL-10 -1082 A > G polymorphism mediates allele-specific transcription via poly(ADP-Ribose) polymerase 1 in macrophages engulfing apoptotic cells.

Abstract excerpt

The biallelic IL-10 single nucleotide polymorphism at -1082 of the promoter region linked to individual variation in cytokine inducibility has been strongly implicated in several pathological conditions including the development of, and outcomes in, septic shock during pneumococcal infection, acu...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Electrophoresis, Polyacrylamide Gel
• Share to Electrophoretic Mobility Shift Assay