Article
Interleukin-10-1082 promoter polymorphism in association with cytokine production and sepsis susceptibility.
Intensive care medicine - 1 Feb 2006
Stanilova Spaska A, Miteva Lyuba D, Karakolev Zhivko T, Stefanov Chavdar S
Abstract excerpt
OBJECTIVE: To investigate the -1082 (A/G) polymorphism in the promoter of the IL-10 gene in terms of IL-10 production from stimulated peripheral blood mononuclear cells (PBMC) and to evaluate the relationship of this polymorphism with susceptibility to severe sepsis and the outcome of the disease. DESIGN: Case-control study. SETTING: Research laboratory of Molecular Biology and Immunology and University Hospital...
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