Article
IL-10 polymorphism is associated with increased incidence of severe sepsis.
Chinese medical journal - 1 Nov 2003
Shu Qiang, Fang Xiangming, Chen Qixing, Stuber Frank
Abstract excerpt
OBJECTIVE: To investigate whether three biallelic polymorphisms at positions -592, -819 and -1082 in the promoter region of the IL-10 gene are associated with increased incidence of severe sepsis. METHODS: The IL-10 -592, -819 and -1082 polymorphisms were typed using polymerase chain reaction followed by digestion with the restriction enzymes RsaI, MaeIII and MnlI, respectively. RESULTS: Patients with severe...
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