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Genetic polymorphisms in folate and alcohol metabolism and breast cancer risk: a case-control study in Thai women.

Breast cancer research and treatment - 1 Oct 2010

Sangrajrang Suleeporn, Sato Yasunori, Sakamoto Hiromi, Ohnami Sumiko, Khuhaprema Thiravud, Yoshida Teruhiko

Abstract excerpt

Dietary folate as well as polymorphic variants in one-carbon metabolism genes may modulate risk of breast cancer through aberrant DNA methylation and altered nucleotide synthesis and repair. Alcohol is well recognized as a risk factor for breast cancer, and interactions with one-carbon metabolism has also been suggested. The purpose of this study is to test the hypothesis that genetic polymorphisms in the folate...

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Source

Identifiers

PMID: 20180013
DOI: 10.1007/s10549-010-0804-4

Genes

DRD2
DRD3
MTR
MTRR
NAT2
ALDH2
GSTP1
MTHFR
NAT1
TYMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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