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Article

Analysis of neuropeptide S receptor gene (NPSR1) polymorphism in rheumatoid arthritis.

PloS one - 22 Feb 2010

D'Amato Mauro, Zucchelli Marco, Seddighzadeh Maria, Anedda Francesca, Lindblad Staffan, Kere Juha, Alfredsson Lars, Klareskog Lars, Padyukov Leonid

Abstract excerpt

BACKGROUND: Polymorphism in the neuropeptide S receptor gene NPSR1 is associated with asthma and inflammatory bowel disease. NPSR1 is expressed in the brain, where it modulates anxiety and responses to stress, but also in other tissues and cell types including lymphocytes, the lungs, and the inte...

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Source

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Identifiers

PMID: 20179762
DOI: 10.1371/journal.pone.0009315
PMCID: PMC2825264

Genes

NPSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20179762-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Analysis of neuropeptide S receptor gene (NPSR1) polymorphism in rheumatoid arthritis.PMID 20179762Read ↗

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Neuropeptide s receptor 1 gene polymorphism is associated with susceptibility to inflammatory bowel disease.Semantic proximity Read ↗

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Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma.Semantic proximity Read ↗

Neuropeptide S receptor induces neuropeptide expression and associates with intermediate phenotypes of functional gastrointestinal disorders.Semantic proximity Read ↗

Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid arthritis.Semantic proximity Read ↗

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