Article
Assessment of the neuropeptide S system in anxiety disorders.
Biological psychiatry - 1 Sept 2010
Donner Jonas, Haapakoski Rita, Ezer Sini, Melén Erik, Pirkola Sami, Gratacòs Mònica, Zucchelli Marco, Anedda Francesca, Johansson Lovisa E, Söderhäll Cilla, Orsmark-Pietras Christina, Suvisaari Jaana, Martín-Santos Rocío, Torrens Marta, Silander Kaisa, Terwilliger Joseph D, Wickman Magnus, Pershagen Göran, Lönnqvist Jouko, Peltonen Leena, Estivill Xavier, D'Amato Mauro, Kere Juha, Alenius Harri, Hovatta Iiris
Abstract excerpt
BACKGROUND: The G protein-coupled receptor neuropeptide S receptor 1 (NPSR1) and its ligand neuropeptide S (NPS) form a signaling system mainly implicated in susceptibility to asthma and inflammatory disorders in humans and regulation of anxiety and arousal in rodents. We addressed here the role...
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