Article
Neuropeptide S receptor induces neuropeptide expression and associates with intermediate phenotypes of functional gastrointestinal disorders.
Gastroenterology - 1 Jan 2010
Camilleri Michael, Carlson Paula, Zinsmeister Alan R, McKinzie Sanna, Busciglio Irene, Burton Duane, Zucchelli Marco, D'Amato Mauro
Abstract excerpt
BACKGROUND & AIMS: NPSR1, the receptor for neuropeptide S (NPS), is expressed by gastrointestinal (GI) enteroendocrine cells, and is involved in inflammation, anxiety, and nociception. NPSR1 polymorphisms are associated with asthma and inflammatory bowel disease. We aimed to determine whether NPS...
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