Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma.

doi:10.1371/journal.pone.0060111

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Article

Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma.

PloS one - 1 Jan 2013

Acevedo Nathalie, Sääf Annika, Söderhäll Cilla, Melén Erik, Mandelin Jami, Pietras Christina Orsmark, Ezer Sini, Karisola Piia, Vendelin Johanna, Gennäs Gustav Boije af, Yli-Kauhaluoma Jari, Alenius Harri, von Mutius Erika, Doekes Gert, Braun-Fahrländer Charlotte, Riedler Josef, van Hage Marianne, D'Amato Mauro, Scheynius Annika, Pershagen Göran, Kere Juha, Pulkkinen Ville

Abstract excerpt

Retinoid acid receptor-related Orphan Receptor Alpha (RORA) was recently identified as a susceptibility gene for asthma in a genome-wide association study. To investigate the impact of RORA on asthma susceptibility, we performed a genetic association study between RORA single nucleotide polymorphisms (SNPs) in the vicinity of the asthma-associated SNP (rs11071559) and asthma-related traits. Because the regulatory...

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Identifiers

PMID: 23565190
DOI: 10.1371/journal.pone.0060111
PMCID: PMC3615072

Genes

RORA
NPSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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