Article
DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory.
The Journal of biological chemistry - 23 Apr 2010
Li Yi, Hu Jie, Höfer Klemens, Wong Andrew M S, Cooper Jonathan D, Birnbaum Shari G, Hammer Robert E, Hofmann Sandra L
Abstract excerpt
A family of integral membrane proteins containing a signature DHHC motif has been shown to display protein S-acyltransferase activity, modifying cysteine residues in proteins with fatty acids. The physiological roles of these proteins have largely been unexplored. Here we report that mice homozyg...
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