Article

Cell-type specific visualization and biochemical isolation of endogenous synaptic proteins in mice

2018-07-12

Abstract excerpt

In recent years, the remarkable molecular complexity of synapses has been revealed, with over 1000 proteins identified in the synapse proteome. Although it is known that different receptors and other synaptic proteins are present in different types of neurons and synapses, the extent of synapse diversity across the brain is largely unknown, mainly owing to technical limitations. Combining mouse genetics and proteo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 33c4a22e-23e7-59b4-b99f-16d9fd983b03
DOI: 10.1101/363614

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cell-type specific visualization and biochemical isolation of endogenous synaptic proteins in miceDOI 10.1101/363614Read

Regional Diversity in the Postsynaptic Proteome of the Mouse BrainSemantic proximity Read

The human and mouse synaptome architecture of excitatory synapses show conserved featuresSemantic proximity Read

Mapping Functional Protein Neighborhoods in the Mouse BrainSemantic proximity Read

Cell type-specific biotin labeling <i>in vivo</i> resolves regional neuronal proteomic differences in mouse brainSemantic proximity Read

Quantitative proteomics and protein network analysis of hippocampal synapses of CaMKIIalpha mutant mice.Semantic proximity Read

Synapse proteomics of multiprotein complexes: en route from genes to nervous system diseases.Semantic proximity Read

NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation.Semantic proximity Read

Proteomics of brain synapses and molecular dissection of synaptic subdomains.Semantic proximity Read

Panel of synaptic protein ELISAs for evaluating neurological phenotype.Semantic proximity Read

Proteomics, ultrastructure, and physiology of hippocampal synapses in a fragile X syndrome mouse model reveal presynaptic phenotype.Semantic proximity Read

Comparing synaptic proteomes across seven mouse models for autism reveals molecular subtypes and deficits in Rho GTPase signalingSemantic proximity Read

Impact of genetic variation on synaptic protein levels in genetically diverse mice.Semantic proximity Read