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Article

Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response.

BMC infectious diseases - 23 Feb 2010

Bittar Cíntia, Jardim Ana Carolina G, Yamasaki Lilian H T, de Queiróz Artur T L, Carareto Claudia M A, Pinho João Renato R, de Carvalho-Mello Isabel Maria V G, Rahal Paula

Abstract excerpt

BACKGROUND: The quasispecies nature of HCV may have important implications for viral persistence, pathogenicity and resistance to antiviral agents. The variability of one of the viral proteins, NS5A, is believed to be related to the response to IFN therapy, the standard treatment for infection. In this study we analyzed the quasispecies composition of NS5A protein in patients infected with HCV genotype 3a, before...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20178583
DOI: 10.1186/1471-2334-10-36
PMCID: PMC2838888

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Source receipt: pubmed, retrieved 7 Sept 2026.

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