Article
Genetic distance and heterogenecity between quasispecies is a critical predictor to IFN response in Egyptian patients with HCV genotype-4.
Virology journal - 14 Feb 2007
Zekri Abdel Rahman N, El-Din Hanaa M Alam, Bahnassy Abeer A, Khaled Mohsen M, Omar Ashraf, Fouad Inas, El-Hefnewi Mahmoud, Thakeb Fouad, El-Awady Mostafa
Abstract excerpt
BACKGROUND: HCV is one of the major health problems in Egypt, where it is highly prevalent. Genotype 4 is the most common genotype of HCV and its response to treatment is still a controversy. METHODS: HCV genotype 4 quasispecies diversity within the 5' untranslated region (5'UTR) was studied in a series of 22 native Egyptian patients with chronic hepatitis C virus with no previous treatment who satisfied all NIH...
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