Article
Relationship between interferon therapy and variability in nonstructural gene 5b of hepatitis C virus.
Journal of gastroenterology - 1 Oct 1998
Tao Q, Wei L, Chang J, Wang H, Sun Y
Abstract excerpt
The hepatitis C virus (HCV) quasispecies nature in the hypervariable region (HVR) has been reported and found to relate to the effectiveness of interferon (IFN) treatment. However, the quasispecies nature in the nonstructural (NS) 5b region remains to be addressed. To examine this characterization and relationship with IFN therapy, we sequenced six independent HCV clones from each of eight patients. The eight...
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