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Article

Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease.

Gut - 1 Feb 2010

Dongiovanni P, Valenti L, Rametta R, Daly A K, Nobili V, Mozzi E, Leathart J B S, Pietrobattista A, Burt A D, Maggioni M, Fracanzani A L, Lattuada E, Zappa M A, Roviaro G, Marchesini G, Day C P, Fargion S

Abstract excerpt

BACKGROUND/AIMS: The aim of this study was to assess the effect of functional ENPP1(ectoenzyme nucleotide pyrophosphate phosphodiesterase 1)/PC-1 (plasma cell antigen-1) and IRS-1 (insulin receptor substrate-1) polymorphisms influencing insulin receptor activity on liver damage in non-alcoholic f...

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Source

Identifiers

PMID: 20176643
DOI: 10.1136/gut.2009.190801

Genes

ENPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20176643-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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