Article
Effect of lectin-like oxidized LDL receptor-1 polymorphism on liver disease, glucose homeostasis, and postprandial lipoprotein metabolism in nonalcoholic steatohepatitis.
The American journal of clinical nutrition - 1 Oct 2011
Musso Giovanni, Cassader Maurizio, De Michieli Franco, Saba Francesca, Bo Simona, Gambino Roberto
Abstract excerpt
BACKGROUND: Nonalcoholic steatohepatitis (NASH) affects 3-5% of the general adult population and predisposes to cirrhosis, cardiovascular disease (CVD), and diabetes through unclear mechanisms. Lectin-like oxidized LDL receptor-1 (LOX-1) has been connected to CVD risk in the general population and to insulin resistance and hepatic fibrogenesis in experimental models. OBJECTIVE: The objective was to assess the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.