Article
Lack of association between peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms and progressive liver damage in patients with non-alcoholic fatty liver disease: a case control study.
BMC gastroenterology - 8 Sept 2010
Dongiovanni Paola, Rametta Raffaela, Fracanzani Anna Ludovica, Benedan Luca, Borroni Vittorio, Maggioni Paolo, Maggioni Marco, Fargion Silvia, Valenti Luca
Abstract excerpt
BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) play key roles in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). AIM: to assess the effect of functional single nucleotide polymorphisms (SNPs) of PPARα and PPARγ2, previously associated with insulin resistance and dys...
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