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Article

Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue

22 Feb 2010

Abstract excerpt

BACKGROUND: A high-sensitivity DNA microarray platform requiring nanograms of RNA input facilitates the application of transcriptome analysis to individual skeletal muscle (SM) tissue samples. Culturing myotubes from SM-biopsies enables investigating transcriptional defects and assaying therapeutic strategies. This study compares the transcriptome of aneurally cultured human SM cells versus that of tissue...

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PMID: 20175888
DOI: 10.1186/1471-2164-11-125

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