Article

Distinct Myogenic Stages Recapitulate Transcriptomic Networks of Skeletal Muscle in COPD Cachexia

2025-12-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Cachexia is an extrapulmonary manifestation of chronic obstructive pulmonary disease (COPD) characterized by weight loss and muscle wasting. Transcriptomic analysis of skeletal muscle may provide insight to COPD-cachexia-relevant dysregulation, including at the mitochondrial level, where dysfunction is a hallmark of muscle wasting. As muscle biopsies are invasive and yield f...

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Literature Corpus work: 37d6b3ee-423a-57bf-8150-b7ed1f193fcd
DOI: 10.64898/2025.12.03.692216

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