Article

A novel skeletal-specific adipogenesis pathway defines key origins and adaptations of bone marrow adipocytes with age and disease

2021-01-06

Abstract excerpt

<h4>SUMMARY</h4> Bone marrow adipocytes (BMAs) accumulate with age and in diverse disease states. However, their age- and disease-specific origins and adaptations remain unclear, impairing our understanding of their context-specific endocrine functions and relationship with surrounding tissues. In this study, we identified a novel, bone marrow-specific adipogenesis pathway using the Adipoq Cre+/DTA+ ‘fat free’ m...

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Literature Corpus work: 236ab754-7102-5aa9-ad05-62c0c0f5b008
DOI: 10.1101/2021.01.05.425449

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