Article
ATM sequence variants associate with susceptibility to non-small cell lung cancer.
International journal of cancer - 15 Nov 2007
Yang Hushan, Spitz Margaret R, Stewart David J, Lu Charles, Gorlov Ivan P, Wu Xifeng
Abstract excerpt
ATM gene mutations have been implicated in many human cancers. However, the role of ATM polymorphisms in lung carcinogenesis is largely unexplored. We conducted a case-control analysis of 556 Caucasian non-small-cell lung cancer (NSCLC) patients and 556 controls frequency-matched on age, gender and smoking status. We genotyped 11 single nucleotide polymorphisms of the ATM gene and found that compared with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
