Article
Systems genetics analysis of gene-by-environment interactions in human cells.
American journal of human genetics - 12 Mar 2010
Romanoski Casey E, Lee Sangderk, Kim Michelle J, Ingram-Drake Leslie, Plaisier Christopher L, Yordanova Roumyana, Tilford Charles, Guan Bo, He Aiqing, Gargalovic Peter S, Kirchgessner Todd G, Berliner Judith A, Lusis Aldons J
Abstract excerpt
Gene by environment (GxE) interactions are clearly important in many human diseases, but they have proven to be difficult to study on a molecular level. We report genetic analysis of thousands of transcript abundance traits in human primary endothelial cell (EC) lines in response to proinflammato...
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