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Article

Automated network analysis identifies core pathways in glioblastoma.

PloS one - 12 Feb 2010

Cerami Ethan, Demir Emek, Schultz Nikolaus, Taylor Barry S, Sander Chris

Abstract excerpt

BACKGROUND: Glioblastoma multiforme (GBM) is the most common and aggressive type of brain tumor in humans and the first cancer with comprehensive genomic profiles mapped by The Cancer Genome Atlas (TCGA) project. A central challenge in large-scale genome projects, such as the TCGA GBM project, is the ability to distinguish cancer-causing "driver" mutations from passively selected "passenger" mutations. PRINCIPAL...

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Identifiers

PMID: 20169195
DOI: 10.1371/journal.pone.0008918
PMCID: PMC2820542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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