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Article

Comparative proteogenomic characterization of glioblastoma

30 Jun 2019

Abstract excerpt

Aim: Glioblastoma multiforme (GBM) carries a dismal prognosis. Integrated proteogenomic analysis was performed to understand GBM pathophysiology. Patients & methods: 17 patient samples were analyzed for driver mutations, oncogenes, major pathway alterations and molecular changes at gene and protein level. Clinical, treatment and survival data were collected. Results: Significantly mutated genes included TP53,...

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Identifiers

PMID: 31290679
DOI: 10.2217/cns-2019-0003

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