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Article

An integrative characterization of recurrent molecular aberrations in glioblastoma genomes.

Nucleic acids research - 1 Oct 2013

Sintupisut Nardnisa, Liu Pei-Ling, Yeang Chen-Hsiang

Abstract excerpt

Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumor in adults. Decades of investigations and the recent effort of the Cancer Genome Atlas (TCGA) project have mapped many molecular alterations in GBM cells. Alterations on DNAs may dysregulate gene expressions and drive malignancy of tumors. It is thus important to uncover causal and statistical dependency between 'effector' molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23907387
DOI: 10.1093/nar/gkt656
PMCID: PMC3799430

Genes

EGFR
GSTM1
PLXNB1

Provenance

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