Article
Elevation of zinc transporter ZnT3 protein in the cerebellar cortex of the AbetaPP/PS1 transgenic mouse.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Zheng Wei, Wang Tao, Yu Dan, Feng Wan-Yu, Nie Ying-Xue, Stoltenberg Meredin, Danscher Gorm, Wang Zhan-You
Abstract excerpt
The presence of senile plaques containing abundant amyloid-beta (Abeta) peptide is one of the major pathological hallmarks of Alzheimer's disease (AD). Recent studies support the notion that overexpression of zinc transporters (ZnT) is involved in zinc metabolic disturbances and Abeta aggregation...
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