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Article

CD40 functional gene polymorphisms and mRNA expression in rheumatoid arthritis patients from western Mexico.

Genetics and molecular research : GMR - 24 Oct 2016

Román-Fernández I V, Ávila-Castillo D F, Cerpa-Cruz S, Gutiérrez-Ureña S, Hernández-Bello J, Padilla-Gutiérrez J R, Valle Y, Ramírez-Dueñas M G, Pereira-Suárez A L, Muñoz-Valle J F

Abstract excerpt

The CD40 pathway is involved in the development and pathogenesis of autoimmune diseases, including rheumatoid arthritis (RA). Two single nucleotide polymorphisms (SNPs) in the CD40 gene, rs1883832 and rs4810485, are associated with susceptibility to inflammatory and autoimmune diseases and are thought to alter CD40 expression at the mRNA and protein level. This study assessed for the first time the association of...

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PMID: 27813548
DOI: 10.4238/gmr15048775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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