Article
A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis.
Arthritis and rheumatism - 1 Oct 2010
Tan Wenfeng, Wu Hui, Zhao Jian, Derber Lezlie A, Lee David M, Shadick Nancy A, Conn Doyt L, Smith Edwin A, Gersuk Vivian H, Nepom Gerald T, Moreland Larry W, Furst Daniel E, Thompson Susan D, Jonas Beth L, Holers V Michael, Glass David N, Chen Pojen P, Bridges S Louis, Weinblatt Michael E, Paulus Harold E, Tsao Betty P
Abstract excerpt
OBJECTIVE: We previously observed the association of the co-occurrence of the HLA-DRB1 shared epitope (SE) and RANKL single-nucleotide polymorphisms (SNPs) with younger age at the onset of rheumatoid arthritis (RA) in 182 rheumatoid factor (RF)-positive European American patients with early-onset...
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