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Article

Gender-specific effects of genetic variants within Th1 and Th17 cell-mediated immune response genes on the risk of developing rheumatoid arthritis.

PloS one - 1 Jan 2013

Cáliz Rafael, Canet Luz María, Lupiañez Carmen Belén, Canhão Helena, Escudero Alejandro, Filipescu Ileana, Segura-Catena Juana, Soto-Pino María José, Expósito-Ruiz Manuela, Ferrer Miguel Ángel, García Antonio, Romani Lurdes, González-Utrilla Alfonso, Vallejo Teresa, Pérez-Pampin Eva, Hemminki Kari, Försti Asta, Collantes Eduardo, Fonseca João Eurico, Sainz Juan

Abstract excerpt

The present study was conducted to explore whether single nucleotide polymorphisms (SNPs) in Th1 and Th17 cell-mediated immune response genes differentially influence the risk of rheumatoid arthritis (RA) in women and men. In phase one, 27 functional/tagging polymorphisms in C-type lectins and MC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24023637
DOI: 10.1371/journal.pone.0072732
PMCID: PMC3758336

Genes

CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24023637-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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